Oxford textbook of pathology:

Includes bibliographical references and index.

The Oxford Textbook of Pathology is a milestone in the development of pathology texts. It comprises the most definitive and comprehensive textbook of general and systematic pathology currently available, and will be indispensable for undergraduate and medical students, postgraduate studentsof pathology, and clinical scientists. Each chapter has been written by a panel of internationally acknowledged experts and incorporates the most recent advances in the field.Readers of the Oxford Textbook of Pathology will also benefit from an exceptionally high standard of design and illustration. The two volumes provide 1090 colour photographs and micrographs; 459 specially commissioned full colour line and tone figures; and 1130 black-and-white photographs. Thetextbook therefore provides a unique aid to learning and identification.The text is in two parts: Volume 1 is devoted to the general principles of pathology. Emphasis is placed on the integration of molecular biology with classic cellular pathology. It incorporates a discussion of normal cell structure, differentiation, and function; there are separate chapters onchromosomal organization and gene regulation; general principles of immunology and immune mechanisms in disease including the pathophysiology of infection and other defence mechanisms; there are two sections on abnormal cell growth including an extensive chapter on neoplasia. Developmental andenvironmental pathology are also covered in this volume. The emphasis throughout has been to correlate well-established general principles and phenomena in pathology with what is now known about underlying cellular and molecular mechanisms.Volume 2 covers the pathology of systems. Here too, care has been taken to integrate the newer techniques, including immunocytochemistry and molecular biology, as they apply to each organ system. Pathology has been described in its clinical context. The approach in each of the system chapters isto describe the normal structure and function followed by a description and analysis of the structural and cellular bases of particular diseases. The pathobiology and clinical consequences of pathological processes are emphasized. The intent is to explain gross structural and microscopicobservations in disease at a molecular level and point out their clinical relevance.