Friedman, Lawrence M.

Fundamentals of clinical trials - 3rd ed. - New York : Springer, 1998. - xviii, 361 p. : ill. ; 24 cm.

Includes bibliographical references and index.

The randomized control clinical trial has become the goal standard scientific methods for the evaluation of pharmaceuticals, biologics, devices, procedures,and diagnostic tests. This trial design has been successfully used in both therapeutic and disease prevention trials. It is superior to alternative design by eliminating several sources of bias which exist in those designs. This role has evolved over the past three decades in a number of disease area including cardiology, ophthalmology, cancer, and AIDS. ,

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Clinical trials.
Clinical Trials.
Research Design.

W 20.5 FF 1991