TY - BOOK AU - Gupta, SK. TI - Basic principles of clinical research and methodology SN - 8184480865 PY - 2007/// CY - New Delhi PB - Jaypee Brothers, KW - Clinical research N1 - Includes bibliographical references and index N2 - In the last decade, there has been a paradigms shift in drug discovery from the days of lab chemistry isolation of actives and synthesis to clinical research. Clinical trials represent a bridge from early stage drug development to commercialization. It takes over billion dollars to bring drugs from the lab to the market time -span - 9 years on average. ER -